Table #: Results of LLNA: Stimulation Index

 

Sample Description

Test or Control Group

Vehicle

Low

Medium

High

Positive Control

Stimulation Index (SI)

 

 

 

 

 

EC3b

 

 

 

 

 

b)  EC3 is the minimum concentration required to elicit a sensitization reaction (interpolated)

 

SI = Group Mean DPM ? Vehicle control mean DPM

EC3 = C + [ (3-D) / (B-D) ] * (A-C)

Where (C,D) fall below SI of 3 (C = concentration, D = SI)

(A,B) fall above  SI of 3 (A = concentration, B = SI)