Table #: Selected haematology, clinical chemistry and pathology findings among mice (at termination)
| Dose level (Unit) | 0 | x | xx | xxx | xxxx | 0 | x | xx | xxx | xxxx |
| male | female | |||||||||
| Number in group | 10 | 10 | 10 | 9 | 9 | 10 | 10 | 10 9 | 9 |
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| Haematology (mean values) |
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| NEU (thousand / mm³) |
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| LYM (thousand / mm³) |
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| BAS (thousand / mm³) |
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| EOS (thousand / mm³) |
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| Clinical chemistry (mean values) |
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| AP(IU/L)# |
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| AST(IU/L) |
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| Gross pathology (incidence) |
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| Liver - discoloration |
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| Histopathology (incidence) |
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| Liver |
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| - necrosis + inflammation |
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| - mononuclear cell infiltrate |
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| Spleen - excess haematopoiesis |
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| Uterus - hydrometra |
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* Linearly related to dose (p < 0.05) with a negative scope (females only).
** (p <0.05) and *** <0.01) vs control
# Linearly related to dose (p <0.05) with a positive scope for males and a negative scope for females