In a 1-year dog study (MRID  if available) Chemical name, (% a.i.)  was administered to [# of dogs; strain]/sex/dose in [diet, water, by capsule, by gavage] at dose levels of (dose levels) ppm (0, , ,    mg/kg bw/day) for (duration).

 

[Describe toxicity briefly.  If no toxicity state that there were no compound related effects in mortality, clinical signs, body weight, food consumption, hematology, clinical chemistry, urinalysis, organ weights, or gross and histologic (including tumours) pathology]The LOAEL is      , based on           .  The NOAEL is  .

 

This study in dogs is [acceptable, unacceptable(why)]  and satisfies (does not satisfy) the guideline requirement for a 1-year oral toxicity study in dogs (OPPTS 870.4100; OECD 452).  [If it does not satisfy the requirement, concisely list only major deficiencies or refer to deficiency section.]