This third webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Thursday 30 January 2020. It focused on the core information and telecommunication technologies applications that were built to support AOP development, management and dissemination. Tools and technical tips to facilitate scientific knowledge assembling and evaluations were also presented. The AOP framework implements a collaborative and innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.

Presentations by:
 

• Nathalie Delrue from the OECD Environment Directorate introduced the presenters and scope of the webinar | Presentation
• Clemens Wittwehr from the European Commission Joint Research Centre provided an introduction on AOP-KB | Presentation
• Dan Villeneuve from the US Environmental Protection Agency provided some tips on the development of AOPs | Presentation
• Holly Mortensen from the US Environmental Protection Agency presented ways of retrieving information from databases and other AOP tools | Presentation

Second webinar on Adverse Outcome Pathways: assembling and evaluating weight of evidence and quantitative understanding

This second webinar in the series of Adverse Outcome Pathways (AOPs) was organised on Wednesday 15 January 2020. It focused on the importance of weight of evidence in the process of developing AOPs, the types and lines of evidences assembled, examples demonstrating the lines of evidence and understanding why quantitative AOPs are developed. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.

Presentations by:

• Magda Sachana from the OECD Environment Directorate introduced the presenters and scope of the webinar | Presentation
• Bette Meek from the University of Ottawa provided an introduction to WoE for AOPs | Presentation
• Kristie Sullivan from the Physicians Committee for Responsible Medicine shared examples of implementing WoE in an AOP | Presentation
• Dan Villeneuve from the US Environmental Protection Agency spoke about quantitative understanding of relationships and why that’s important | Presentation.

FIRST WEBINAR ON ADVERSE OUTCOME PATHWAYS (AOPS): AOP FRAMEWORK

On 30 April 2019, the OECD organised a webinar on the Adverse Outcome Pathway (AOP) framework. The AOP framework is a collaborative tool that applies an innovative approach for collecting mechanistic knowledge from various sources that can eventually support chemical safety assessment.

The following questions were addressed:

• What is the AOP framework and why should you care?
• Why are we developing AOPs?
• Why collaborations are encouraged and why should scientific societies be brought in?
• What are the opportunities for collaboration in AOP development?
  
  

Speakers:

• Nathalie Delrue (OECD Secretariat): OECD AOP Programme | Presentation
• Catherine Willett (Humane Society International): An Introduction to AOP framework | Presentation
• Jason O’Brien (Environment Canada): AOP collaborative development | Presentation
• Dan Villeneuve (US Environmental Protection Agency): Examples of AOP application in chemical risk assessment | Presentation