Testing of chemicals

Presentation by Endpoints: Section 4 - Health Effects

 

The Test Guidelines of Section 4 on Health Effects and related documents have been organised by the type of hazard. With nearly 70 Test Guidelines available in Section 4 of the OECD Guidelines for the Testing of Chemicals and approximately the same number of related documents published in the series on Testing and Assessment, this presentation enables easy and quick access to the:

  • various Test Guidelines available for a given endpoint
  • general documents available for a given endpoint
  • documents specifically developed for a given Test Guideline

 

Types of Hazard

Endocrine Disrupters

General Documents
    
Conceptual Framework
The Test Guidelines included in the OECD Conceptual Framework (CF) for Testing and Assessment of Endocrine Disrupters
and associated documents published in the series on Testing and Assessment - can be obtained from the simplified CF below.  This only addresses Mammalian Toxicology.  References related to Non-Mammalian Toxicology can be found on the Presentation by Endpoints: Section 2 page.

Level 2: In vitro assays providing data about selected endocrine mechanism(s)
Level 3: In vivo assays providing data about selected endocrine mechanism(s)
Level 4: In vivo assays providing data on adverse effects on endocrine relevant endpoints
Level 5: In vivo assays providing more comprehensive data on adverse effects on endocrine relevant endpoints
over more extensive parts of the life cycle of the organism

 

 

 

 

 

 

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