Latest Documents


  • 7-November-2018

    English

    Series on Testing and Assessment: publications by number

    The purpose of this Series is to provide up-to-date information on the OECD activities related to testing and assessment of chemicals.

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  • 6-November-2018

    English

    Draft Guidance and Review Documents/Monographs

    Deadline for comments: Draft Guidance Document on Aquatic and Sediment Toxicological Testing of Nanomaterials by 30 October 2018.

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  • 24-October-2018

    English

    Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

    The first report describes the linkage between inhibition of complex I of the mitochondrial respiratory chain and motor deficit as in parkinsonian disorders. The second report links chronic binding of antagonist to N-methyl-D-aspartate receptors during brain development leading to neurodegeneration. The third report details the linkage between binding and activation of androgen receptor leading to reproductive dysfunction.

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  • 22-October-2018

    English

    OECD Test Guidelines for the Chemicals

    The OECD Guidelines are a unique tool for assessing the potential effects of chemicals on human health and the environment. Accepted internationally as standard methods for safety testing, the Guidelines are used by professionals in industry, academia and government involved in the testing and assessment of chemicals. These Guidelines are regularly updated with the assistance of thousands of national experts from OECD member countries.

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  • 19-October-2018

    English

    Section 4: Health Effects

    Deadlines for comments of OECD Guideline For The Testing Of Chemicals.

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  • 11-October-2018

    English

    Mutual Acceptance of Data (MAD)

    The OECD has developed the Mutual Acceptance of Data (MAD), a multilateral agreement which allows participating countries (including non members) to share the results of various non-clinical tests done on chemicals using OECD methods and principles. MAD reduces duplicative testing, allows governments to work together when assessing chemicals, and saves government and industry resources.

  • 4-September-2018

    English

    Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption

    This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals. The document is intended to provide guidance for evaluating chemical using standardised test guidelines.

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  • 4-September-2018

    English

    Series on Testing and Assessment: Testing for Endocrine Disrupters

    The series on endocrine disrupters provides common tools and guidances for testing the effects of endocrine disrupting chemicals on the oestrogen, androgen and thyroid hormone systems. Using these validated methodologies, regulatory authorities can use internationally harmonised tools to evaluate chemicals of concern for human health and/or the environment as well as testing costs.

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  • 4-September-2018

    English

    OECD Work Related to Endocrine Disrupters

    The OECD has published the Revised Guidance Document 150 on Standardised Test Guidelines for Evaluating Chemicals for Endocrine Disruption originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.

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  • 4-September-2018

    English

    Guidance Document on Good In Vitro Method Practices (GIVIMP)

    GIVIMP aims to reduce the uncertainties in cell and tissue-based in vitro method derived predictions by applying good scientific, technical and quality practices from method development to implementation for regulatory use. Test method developers and test guideline users will find best practices for designing guideline in vitro methods, carrying out safety tests and assuring quality and scientific integrity of the resulting data

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