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Testing of chemicals

Good Laboratory Practice (GLP)

 

The OECD Principles of Good Laboratory Practice (GLP) ensure the generation of high quality and reliable test data related to the safety of industrial chemical substances and preparations. The principles have been created in the context of harmonising testing procedures for the Mutual Acceptance of Data (MAD).

 

Mutual Acceptance of Data

The MAD system helps to avoid conflicting or duplicative national requirements, provides a common basis for co-operation among national authorities and avoids creating non-tariff barriers to trade. OECD countries and full adherents have agreed that a safety test carried out in accordance with the OECD Test Guidelines and Principles of Good Laboratory Practice in one OECD country must be accepted by other OECD countries for assessment purposes. This is the concept of “tested once, accepted for assessment everywhere*”. This saves the chemicals industry the expense of duplicate testing for products which are marketed in more than one country. 

* While the receiving government must accept the study, how it interprets study results is its own prerogative. 

 

Did you know?

By reducing duplication, and creating a framework for the sharing of work, the MAD system saves governments and industry around €150,000,000 each year, as well as reduces the number of animals used in such testing.

 


 Good Laboratory Practice

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 Mutual Acceptance of Data (MAD)

    
 Documents


 OECD Council Acts related to MAD


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