Chemical safety and biosafety

OECD publishes new and updated Test Guidelines for effects on human health and on environmental species

 

The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by

  • government
  • industry
  • independent laboratories


to identify and characterise potential hazards of chemicals. 

Every year new and updated Test Guidelines are adopted to meet the regulatory needs in OECD member countries.


In July 2016, the OECD adopted the following new Test Guidelines - for effects on human health (in vitro skin sensitisation and endocrine disrupter screening) and on mollusc toxicity testing and - on soil and avian toxicity testing, skin corrosion, reproductive toxicity screening, endocrine disrupter screening and genotoxicity testing.

NEW Test Guidelines for effects on human health (in vitro skin sensitisation and endocrine disrupter screening) and on mollusc toxicity testing

  • Test No. 242: Potamopyrgus antipodarum Reproduction Test
  • Test No. 458: Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals 
  • Test No. 442E: In Vitro Skin Sensitisation
  • Test No. 243: Lymnaea stagnalis Reproduction Test

 

Updated Test Guidelines on soil and avian toxicity testing, skin corrosion, reproductive toxicity screening, endocrine disrupter screening, genotoxicity testing

  • Test No. 220: Enchytraeid Reproduction Test
  • Test No. 222: Earthworm Reproduction Test (Eisenia fetida/Eisenia andrei)
  • Test No. 223: Avian Acute Oral Toxicity Test 
  • Test No. 226: Predatory mite (Hypoaspis (Geolaelaps) aculeifer) reproduction test in soil
  • Test No. 228: Determination of Developmental Toxicity to Dipteran Dung Flies(Scathophaga stercoraria L. (Scathophagidae), Musca autumnalis De Geer (Muscidae))
  • Test No. 232: Collembolan Reproduction Test in Soil
  • Test No. 421: Reproduction/Developmental Toxicity Screening Test
  • Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test
  • Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) test method
  • Test No. 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists
  • Test No. 473: In Vitro Mammalian Chromosomal Aberration Test
  • Test No. 474: Mammalian Erythrocyte Micronucleus Test
  • Test No. 475: Mammalian Bone Marrow Chromosomal Aberration Test
  • Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes
  • Test No. 478: Rodent Dominant Lethal Test
  • Test No. 483: Mammalian Spermatogonial Chromosomal Aberration Test
  • Test No. 487: In Vitro Mammalian Cell Micronucleus Test
  • Test No. 489: In Vivo Mammalian Alkaline Comet Assay
  • Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene

 

THE PROGRAMME

 

Related Documents