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30/01/2013 –The first update to the third generation of the QSAR Toolbox (version 3.1) has now been released containing improved search functionalities, interface improvement, a new database for observed rat in vivo metabolism; updated auto oxidation and metabolism simulators; updated DNA binding profiler and additional ways of expressing mixtures composition.
30/01/2013 – Recently the OECD release the third generation of the QSAR Toolbox. The existing tutorials and videos have now been updated according to the new version of the QSAR Toolbox to help the user building categories that are mechanistically and structurally robust to maximise success in filling data gaps for the endpoint of interest. Mid next year the OECD is planning to release additional training material.
This document provides guidance on conducting laboratory tests to determine and assess the efficacy of test substances and/or the effectiveness of test products used as baits for the control of cockroach species in indoor environments.
US Environmental Protection Agency derived the Human health benchmarks for pesticides by applying the health effects data from pesticide registrations to the typical methods used for developing drinking water health advisories. It was developed to enable states, water systems and the public to better determine whether the detection of a pesticide in drinking water or source waters for drinking water may indicate a potential health risk.
This document outlines the current status of and available guidance documents/tools on the application, use and presentation of PRTR data in OECD member countries and the Commission for Environmental Co-operation based on the results of a survey conducted in November 2011.
This document includes a table which summarises descriptions of existing models and tools used for exposure assessment, as well as responses to a 2010 survey – conducted by the OECD Task Force on Exposure Assessment - upon which the table was based. The summary table and the responses are also available in the OECD Environmental Risk Assessment Toolkit (http://envriskassessmenttoolkit.oecd.org/).
This document presents the outcomes of the 3rd OECD Biopesticide Seminar, held in 2011, that focused on the topic of “botanicals” (also known as plant extracts). The Seminar reviewed a number of scientific and regulatory issues related to the “characterisation and analyses of botanicals for the use in plant protection products”.
The OECD Environmental Risk Assessment Toolkit describes the work flow for environmental risk assessment and management of chemicals with links to available OECD material relevant for the different steps in risk assessment and management. This new version of the Toolkit is more interactive and has added functionalities. It will be populated with additional tools and case studies in the future.
The aquatic life benchmarks (for freshwater species) are based on toxicity values reviewed by EPA and used in the Agency's most recent risk assessments developed as part of the decision-making process for pesticide registration. Each Aquatic Life Benchmark is based on the most sensitive, scientifically acceptable toxicity endpoint available for a given taxon of all scientifically acceptable toxicity data available to EPA.
Governments and the chemical industry spend millions of dollars every year testing the safety of chemicals that people use in their everyday lives. Computer modelling, through the OECD-designed QSAR Toolbox software, now replaces many of the tests traditionally done in the laboratory. This allows regulators and industry to save money and use fewer animals to predict the hazardous properties of chemicals.