This guidance is intended to harmonise the way non-guideline in vitro test methods are described. This should in future facilitate an assessment of the relevance of test methods for biological activities and responses of interest, of the quality of data produced, irrespective of whether these tests are based on manual protocols or assay protocols adapted for use on automated platforms or high-throughput screening systems (HTS).
An IT system to develop and evaluate Adverse Outcome Pathways (AOP), the AOP Wiki, has been developed for testing by the Extended Advisory Group on Molecular Screening and Toxicogenomics and by AOP developers included in the work plan. The Wiki provides developers the necessary steps to capture scientific information in a user-friendly manner. The project is jointly led by the ECJRC and the USEPA.
OECD countries have developed PRTR system to track releases and transfers of potentially harmful chemicals. To improve PRTR system, OECD have analysed common elements (pollutants, sectors) in different PRTR systems, mainly focus on institutional arrangement. This serves as a common framework for different PRTR system, and supporting materials for a country that intends to develop or update its PRTR.
PRTR have been established throughout the world to track releases and transfers of potentially harmful chemicals. But most of the PRTR systems were designed without considering comparability, each PRTR has its own requirement of reporting chemicals and sectors. To harmonise globally, OECD reviewed the reporting chemicals and sectors across PRTR systems and produced proposal for harmonised lists of reporting pollutants.
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A cooperative global approach to the regulation of agricultural pesticides and sustainable pest management. Pesticides are widely used in agriculture and have considerable benefits by contributing to a sustainable production of food and feed. If used improperly or in an inappropriate manner, they also can present unacceptable risks to human and animal health and to the environment.
The OECD Advisory Group on Endocrine Disrupters Testing and Assessment met on 16-17 October 2014 in Paris to discuss the development and update of Test Guidelines and related documents for endocrine disrupters testing and assessment.
The OECD has published a report on a pilot chemical classification exercise undertaken in 2013 and ‘14. Using a number of chemical assessments agreed in the OECD hazard assessment programme, reasons why classification proposals may differ were investigated. The report concludes on the main reasons for such differences, and recommends some measures to overcome some of them.
On 26 September 2014, the OECD Council adopted three new, five updated and one corrected OECD Test Guidelines for the testing of chemicals.
This advisory document provides guidance on how pathology peer reviews should be planned, conducted and reported within the context of OECD Good Laboratory Practice.
The OECD is pleased to announce, together with the U.S Environmental Protection Agency and the European Commission Joint Research Centre, the Adverse Outcome Pathway Knowledge Base (AOP KB). This is a web-based platform which aims to bring together all the knowledge on how chemicals can induce adverse effects, therefore providing a focal point for AOP development and dissemination.