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  • 13-November-2019

    English

    Pharmaceutical Residues in Freshwater - Hazards and Policy Responses

    This report calls for a better understanding of the effects of pharmaceutical residues in the environment, greater international collaboration and accountability distribution, and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians, and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance, linked to the overuse of antibiotics, has rapidly escalated into a global health crisis.Unless adequate measures are taken to manage the risks, pharmaceutical residues will increasingly be released into the environment as ageing populations, advances in healthcare, and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective, life-cycle approach to managing pharmaceuticals in the environment. A policy mix of source-directed, use-orientated and end-of-pipe measures, involving several policy sectors, can help to improve health and protect the environment.
  • 6-November-2019

    English

    Safety Assessment of Foods and Feeds Derived from Transgenic Crops, Volume 3 - Common bean, Rice, Cowpea and Apple Compositional Considerations

    This volume compiles the consensus documents developed by the OECD Working Group for the Safety of Novel Foods and Feeds from 2015 to 2019. It deals with the composition of common bean, rice, cowpea and apple, four important crops for agriculture and food consumption worldwide. The science-based information collated here is intended for use during the regulatory assessment of food/feed products derived from modern biotechnology, i.e. issued from transgenic plants. Compositional considerations are provided for each species, including tables detailing the key nutrients, anti-nutrients, possible toxicants, allergens and other metabolites contained in the products. This essential information and solid data can be used in the comparative approach as part of the novel food/feed safety assessment. It should be of value to crop breeders and applicants for commercial uses of novel foods and feeds, to regulators and risk assessors in national authorities, as well as the wider scientific community. More information can be found at BioTrack Online.
  • 23-October-2019

    English

    Series on Testing and Assessment: publications by number

    This document is intended to provide universal Guiding Principles that should be considered when developing or augmenting systematic approaches to Weight of Evidence (WoE) for chemical evaluation and Key Elements to formulating a systematic approach to WoE. The ultimate goal is to facilitate that regulators follow a consistent, clear and transparent delivery of evidence using the Principles and Elements described in this document.

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  • 15-October-2019

    English

    Safety of novel foods and feeds and on the harmonisation of regulatory oversight in biotechnology

    A major fruit crop of temperate regions, APPLE is consumed worldwide as fresh fruit, juice and other food products. This consensus document provides science-based key insights for the regulatory assessment of the environmental safety of genetically-engineered products: taxonomy, reproductive biology, genetics, hybridisation and introgression, and ecology.

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  • 11-October-2019

    English

    Webinar Series on Testing and Assessment Methodologies

    On 27 September 2019, Anne Gourmelon of the Environment Directorate presented an overview of the various alternative test methods developed as OECD Test Guidelines and relevant guidance material to address eye irritation and serious eye damage for hazard classification of chemicals.

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  • 7-October-2019

    English

    Webinar video recording on Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge

    On Thursday 26 September 2019, the OECD discussed "Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge" with the participation of W.L. Gore & Associates, Inc. Presenters shared efforts, successes and challenges in eliminating per and polyfluorinated chemicals of environmental concern from the life cycle of consumer products.

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  • 26-September-2019

    English

    Webinar: Finding Alternatives to Per- and Polyfluoroalkyl Substances of Concern: A Difficult and Continuing Challenge

    Join us on Thursday 26 September 2019 @ 1 pm (CEST, Paris time) / 7 am (EDT time) to learn about efforts, successes and challenges in eliminating per and polyfluorinated chemicals of environmental concern from the life cycle of consumer products.

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  • 10-September-2019

    English

    Children’s Health

    This report aims to enhance awareness for inclusion of children’s exposure in risk assessments when relevant and presents a children’s exposure decision tree that facilitates such decisions. The decision tree can be used to identify if a separate exposure assessment is needed with regard to children, and also aims to identify whether the exposure assessment conducted for adults already provides an acceptable level of safety of children.

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  • 9-September-2019

    English

    Integrated Approaches to Testing and Assessment (IATA)

    Two new cases have been published that focus on use of metabolism information to support read-across and use of a combination of novel methods to identify potential endocrine disruptors, respectively. In addition a considerations document includes lessons and learnings from analysis across case studies and an analysis of uncertainties in six read-across cases.

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  • 19-August-2019

    English

    Adverse Outcome Pathways, Molecular Screening and Toxicogenomics

    Latest releases: AOPs are the central element of a toxicological knowledge framework, promoted by member countries through OECD, built to support chemical risk assessment based on mechanistic reasoning. Seven New AOPs have now been published.

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