Version 4.0 of the QSAR Toolbox has just been released including automated and standardised workflows for skin sensitisation and short-term toxicity to fish, improved customisable reports, modernised and renewed IT system, expansion of databases and the introduction of the reliability score for alerts and databases and enhanced ADME information and improved presentation.
The new OECD report on "Economic Features of Chemical Leasing" is a review of the literature on the economic features of the Chemical Leasing, focusing on the drivers and barriers and comparing its functioning to traditional contracts.
GLP issues raised by testing labs are covered in this comprehensive list of questions and answers, recently updated with questions related to Validation of Software Programmes which Support OECD Test Guidelines
Guidance on principles for reporting defined approaches within IATA and an associated template have been published. A second guidance document illustrates how the reporting templates can be used to document a number of defined approaches (and information sources used within) in the area of skin sensitisation. This is exemplified via 12 case studies for skin sensitisation.
New OECD report highlights facility ageing as a multi-aspect phenomenon. One of the best known aspects of ageing is physical ageing of equipment, but this is just one facet of ageing facilities and only one associated risk factor. Everything related to a site and its processes can age, including equipment, people, procedures and technology. The report also lists potential risk drivers drawn from analysis of ageing-related accidents.
Results of a joint pilot project of the OECD and the UN Sub-Committee of Exports on the Globally Harmonised System of Classification and Labelling of Chemicals (UNSCEGHS) including a report of the results of the pilot and non-biding proposed classifications for three substances.
Participants from 15 countries attended the Workshop on Developmental Neurotoxicity: The use of non-animal test methods for regulatory purposes” on 18 October 2016, in Belgium. The event, co-organised by the OECD and the European Food Safety Authority (EFSA), focused on opportunities and challenges related to alternative methods for testing and assessing the DNT potential of chemicals.
The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. Every year new and updated Test Guidelines are adopted to meet the regulatory needs in OECD member countries. The most recent Test Guidelines were adopted in July 2016.
France has improved its environmental performance over the last decade, lowering greenhouse gas emissions, reducing some air pollutants and cutting its use of fresh water. Further effort will be needed, however, to reduce pollution by nitrates and pesticides and meet ambitious renewable energy targets, according to a new OECD report.
German database Information system für gefährliche Stoffe IGS is now linked to eChemPortal. The IGS provides public access to a variety of information on chemical and microbiological substances mostly in German. The focus is on regulatory information reflecting German and European, as well as Swiss, US and selected other legislation and assessments. Beside this, information on substance data and emergency procedures is available.