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A cooperative global approach to the regulation of agricultural pesticides and sustainable pest management. Pesticides are widely used in agriculture and have considerable benefits by contributing to a sustainable production of food and feed. If used improperly or in an inappropriate manner, they also can present unacceptable risks to human and animal health and to the environment.
The OECD Advisory Group on Endocrine Disrupters Testing and Assessment met on 16-17 October 2014 in Paris to discuss the development and update of Test Guidelines and related documents for endocrine disrupters testing and assessment.
The OECD has published a report on a pilot chemical classification exercise undertaken in 2013 and ‘14. Using a number of chemical assessments agreed in the OECD hazard assessment programme, reasons why classification proposals may differ were investigated. The report concludes on the main reasons for such differences, and recommends some measures to overcome some of them.
On 26 September 2014, the OECD Council adopted three new, five updated and one corrected OECD Test Guidelines for the testing of chemicals.
This Test Guideline is a screening method for the evaluation of ready biodegradability of chemicals.
The test substance, normally at 20 mg C/L, as the sole source of carbon and energy, is incubated (during 28 days normally) in sealed bottles with aerobic condition containing a buffer-mineral salts medium, which has been inoculated with a mixed population of micro-organisms. In order to check the test procedure, a reference substance (aniline, sodium benzoate or ethylene glycol and 1-octanol) of known biodegradability should be tested in parallel. It is recommended that triplicate bottles be analysed after a sufficient number of time intervals. Also at least five test bottles (from test vessels, blank controls, and vessels with the reference substance) are analysed at the end of the test, to enable 95% confidence intervals to be calculated for the mean percentage biodegradation value. The CO2 evolution resulting from the ultimate aerobic biodegradation of the test substance is determined by measuring the Inorganic Carbon (IC) produced in the test bottles in excess of that produced in blank vessels containing inoculated medium only. The extent of biodegradation is expressed as a percentage of the theoretical maximum IC production (ThIC), based on the quantity of test substance added initially. Biodegradation >60% ThIC within the 10-d window in this test demonstrates that the test substance is readily biodegradable under aerobic conditions.
This advisory document provides guidance on how pathology peer reviews should be planned, conducted and reported within the context of OECD Good Laboratory Practice.
The OECD is pleased to announce, together with the U.S Environmental Protection Agency and the European Commission Joint Research Centre, the Adverse Outcome Pathway Knowledge Base (AOP KB). This is a web-based platform which aims to bring together all the knowledge on how chemicals can induce adverse effects, therefore providing a focal point for AOP development and dissemination.
This report presents the results of a survey on Regulatory Regimes for Manufactured Nanomaterials in various OECD jurisdictions with a focus on future regulatory challenges and collaboration among countries.
This document presents the results of the workshop on children’s exposure to chemicals on 7-8 October 2013 in Utrecht, the Netherlands. The main outcomes are 1) a decision tree to enable risk assessors to decide when they should perform children specific exposure and risk assessment, and 2) recommendations for further work on specific exposure assessment issues.
This document is the report of the “OECD Workshop on Integrated Pest Management (IPM) -
Strategies for the adoption and implementation of IPM in agriculture contributing to the sustainable use of
pesticides and to pesticide risk reduction”, that took place on 16 19 October 2011, in Berlin, Germany, and
was chaired by Dr. Wolfgang Zornbach of the German Federal Ministry of Food, Agriculture and
The developed detailed recommendations for promoting and facilitating the adoption and implementation of IPM strategies and for encouraging appropriate stakeholders to use IPM tools and measures. The workshop was planned in the framework of the “OECD Strategic Approach in Pesticide Risk Reduction”. It addressed the following four main issues: technology and Information, economics and market access, policies and strategies and measurements and impact. This report includes the outcomes of the workshop discussions, as well as the overall workshop conclusions (Section 4) and recommendations (Section 5) targeted at governments, all stakeholders and OECD.